Aims: Malignant pleural mesothelioma (MPM) is a rare malignancy with dismal prognosis. While [ epithelioid malignant pleural mesothelioma ] is associated with more favorable outcome, additional factors are needed to further stratify prognosis and to identify patients who can benefit from multimodal treatment. As [ epithelioid malignant pleural … [Read more...]
Asbestos Warnings Grow With Penn State Lawsuit, National Push
Peter Labosky Jr. had been retired for 12 years from his job as a professor of wood sciences at Penn State University when he was diagnosed in 2014 with mesothelioma. He died five months later. [This case is an example of a "new" or non-traditional asbestos litigation area.] Mr. Labosky’s family alleges in a lawsuit filed in 2016 that the … [Read more...]
Malignant mesothelioma of the tunica vaginalis testis: a rare case and review of literature
Background: Malignant mesothelioma of the tunica vaginalis is a rare tumour which comprises less than 1% of all mesotheliomas. Case presentation: 69-years old patient with painful hard mass and hydrocele in the right scrotum to whom a right hydrocelectomy was performed. Any history of scrotal trauma or exposure to asbestos was not present. … [Read more...]
Philly School District poised to pay $850K to teacher diagnosed with mesothelioma
Lea DiRusso, the career city teacher diagnosed last year with a deadly asbestos-linked cancer, is in line to be paid $850,000 by the Philadelphia School District. The school board on Thursday night will consider a resolution allowing the district “to execute, deliver, and perform a settlement agreement” with DiRusso and Amr Osman, her husband, … [Read more...]
Lurbinectedin as Second- or Third-Line Palliative Therapy in Malignant Pleural Mesothelioma
BACKGROUND: Systemic second- and third-line therapies for malignant pleural mesothelioma (MPM) result in a median progression-free survival (mPFS) of <2 months and median overall survival (mOS) of 6-9 months. Lurbinectedin binds to the regulatory region DNA whilst inhibiting tumour-associated macrophage transcription. In early trials, … [Read more...]
Malignant Diffuse Mesothelioma in Women — A Study of 354 Cases
We reviewed 354 cases of malignant diffuse mesothelioma (MM) in women from a database of 2858 histologically confirmed MM cases. There was a pleural predominance with 78% [ pleural malignant mesothelioma ] and 22% [ peritoneal malignant mesothelioma ]. The pleural tumors consisted of 72% epithelioid, 19% biphasic, and 9% sarcomatoid variant. The … [Read more...]