Age alone should not be an exclusion criterion for extended pleurectomy decortication among elderly patients with malignant pleural mesothelioma, according to a review of prospectively collected data presented at the European Lung Cancer Conference.
However, a thorough presurgical assessment of nodal disease and fitness is necessary before older patients undergo adjuvant chemotherapy, according to the researchers. These factors appeared to have a greater negative impact in older patients than younger patients.
Extended pleurectomy decortication (EPD) has been preferred over extrapleural pneumonectomy for patients with malignant pleural mesothelioma who meet strict criteria, according to the researchers.
Although EPD has shown feasibility for elderly patients, debate continues regarding the efficacy of this procedure for older patients.
Annabel J. Sharkey, MBChB , a thoracic surgeon at Glenfield Hospital in Leicester, United Kingdom, and colleagues sought to review data regarding EPD safety and efficacy for elderly patients.
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