New Medical Journal Article Presents Two Case Reports Involving Pericardial Mesothelioma And Suggests This Type Of Malignant Mesothelioma Is Not Always Related To Asbestos Exposure

From a summer 2013 edition of Case Reports in Oncological Medicine we get an interesting article about two patients diagnosed with pericardial malignant mesothelioma.

The first case involved a 57-year old man with a two-month history of dyspnea on exertion and dizziness and three days of rapidly progressive dyspnea. His past medical history was unremarkable.

The second case a 27-year-old man presented with chest pain and was treated as tuberculous pericarditis because he presented with constrictive pericarditis with lymphocytic pericardial effusion. His past medical history was unremarkable, also.

From this recent medical journal article, “Malignant Mesothelioma of the Pericardium: A Report of Two Different Presentations”:


Malignant mesothelioma of the pericardium is a rare and fatal condition that clinicians should be aware of due to its variability of clinical manifestation. The diagnosis may be delayed as a result of delayed treatment. Here, we report two cases of malignant pericardial mesothelioma with two different clinical aspects: cardiac tamponade and mimic tuberculous pericarditis. Both patients: may have indirect exposure to asbestos. Despite chemotherapy, both patients died at 2 weeks and 3 months after the diagnosis. Malignant mesothelioma of the pericardium is fatal, has a variety of presentation, and may not be related to asbestosis exposure.

1. Introduction

Malignant pericardial mesothelioma is extremely rare and has poor prognosis. It accounted for only 0.3% of mesothelioma death worldwide. Unlike pleural mesothelioma, the relationship between asbestos and this lethal tumor is unclear. Patients usually present with dyspnea on exertion caused by pericardial effusion or heart failure. The characters of pericardial effusion, however, may be different such as cardiac tamponade or constrictive pericarditis. Here, we reported two patients diagnosed as pericardial malignant mesothelioma with two different presentations….

4. Conclusion

Malignant mesothelioma of the pericardium is fatal, has a variety of presentation, and may not be related to asbestosis exposure. CT scan of enhanced soft tissue nodules infiltrating the pericardium may be a clue for diagnosis.

[footnotes omitted]

This medical article also points out that “no standard treatment guideline for pericardial mesothelioma has been established yet.”

We will continue to monitor the medical journals for reports about developments concerning the treatment of malignant mesothelioma, be it for the pleural, peritoneal, or pericardial type of “meso” (as it is sometimes called).

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  1. When the PET scan, all other scans, symptoms and occupation lead to this diagnosis and nobody will listen what do you do?

    • Who will help when all PET scans, CT scans, test, symptoms, 22 years in the army as a motor sgt handling asbestos brake pads and clutches, and not one dr will listen and I have documentation! So what am I to do now???????

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