Medical Study Shows Factors That May Negatively Affect Pleural Mesothelioma Survival Time Include Older Age, Histologic Type, And Leukocytosis

In 2013 The Journal of Thoracic and Cardiovascular Surgery published an article “Outcome and prognostic factors of pleural mesothelioma after surgical diagnosis and/or pleurodesis” which identified some factors that may influence the average time a person might live after after being diagnosed with mesothelioma of the pleura (lung). The findings set forth in this medical journal article were presented in part at the Congress of French Society of Thoracic and Cardiovascular Surgery, in Paris, France, on December 9, 2011.

From the Abstract for this relatively recent medical study article:

Objective: The objective of this study was to evaluate long-term survival and prognostic factors in patients with malignant pleural mesothelioma.

Methods: All consecutive patients referred for surgical diagnosis and/or pleurodesis for malignant pleural mesothelioma between 2000 and 2010 were studied. The following parameters were prospectively recorded: age, sex, tobacco consumption, asbestos exposure, type and duration of symptoms, American Society of Anesthesiologists (ASA) score, body mass index, preoperative C-reactive protein levels, white blood cells and platelet count, pachypleuritis on chest radiograph, type of diagnostic surgical procedure, histologic type, modality of pleurodesis, and chemotherapy….

Conclusions: Median survival in an unselected population of patients with malignant pleural mesothelioma treated nonsurgically is 12 months. Nonepithelioid histology, older age, abnormal C-reactive protein levels, and leukocytosis are independent predictors of worse survival.

We will continue to monitor this medical journal and others for reports about survival time after mesothelioma diagnosis.

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