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UH researcher leads breakthrough on a deadly cancer

By Star-Advertiser staff

POSTED: 07:46 p.m. HST, May 06, 2012

An international team led by University of Hawaii Cancer Center researcher Haining Yang has identified a protein known as HMGB1 as a critical link in the development of malignant mesothelioma, one of the deadliest forms of cancer.

The findings were published in the current issue of the online journal “Cancer Research.”

Mesothelioma has been linked to occupational and environmental exposure to asbestos and the naturally occurring mineral fiber erionite. The average survival for those diagnosed with the disease is less than one year, in part because the cancer is highly aggressive and resistant to current treatments, and partly because it is usually diagnoses it its late states.

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